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SASInstitute A00-282 : Clinical Trials Programming Using SAS 9.4

A00-282

Exam Code: A00-282

Exam Name: Clinical Trials Programming Using SAS 9.4

Updated: Sep 09, 2026

Q & A: 144 Questions and Answers

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SASInstitute A00-282 Exam Syllabus Topics:

SectionObjectives
Regulatory and Clinical Research Concepts- Clinical trial workflow
  • 1. Study design fundamentals
    • 2. Regulatory submission basics
      Clinical Trials Data Standards- CDISC Standards
      • 1. SDTM structure and implementation
        • 2. ADaM datasets and analysis-ready data
          SAS Programming for Clinical Trials- Reporting and Analysis
          • 1. Listings, tables, and figures generation
            • 2. Statistical reporting with SAS procedures
              - Data Management
              • 1. Data cleaning and transformation
                • 2. Dataset merging and manipulation

                  SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

                  Question #1

                  Review the following procedure code:
                  proc ttest data=DATA1;
                  class GROUPVAR1;
                  var VAR1;
                  run;
                  Which variable is most appropriate to be analyzed as variable VAR1?

                  A. Treatment, with possible values of "Placebo" or "Active"
                  B. Systolic blood pressure, with possible values of "<120", "120 - 139", "140 - 159", "160 - 179", and
                  "180+"
                  C. Number of infections, with possible values of 0, 1, or 2
                  D. Age, with possible values of any integer between and including 18 and 65


                  Question #2

                  The following SAS program is submitted, but fails due to syntax errors.

                  What is the cause of the syntax errors?

                  A. The keep= data set option should be (keep=MonthExp).
                  B. An array can only be referenced in a KEEP statement and not within a keep= data set option.
                  C. An array cannot be referenced on a keep= data set option.
                  D. The keep= data set option should be (keep=MonthExp*).


                  Question #3

                  Identify the data structure with the following characteristics:
                  - Contains one or more records per subject, per analysis parameter, and per analysis timepoint.
                  - May be derived from findings, events, interventions and special-purpose SDTM domains, or other ADaM datasets.
                  - A record can represent an observed, derived, or imputed value required for analysis.

                  A. Subject Level Analysis Data Set (ADSL)
                  B. Event Level Analysis Data Set (ADAE)
                  C. General Data Structure (GDS)
                  D. Basic Data Structure (BDS)


                  Question #4

                  Given the following demographic dataset:

                  Which program will generate a report where observations will appear in order by SITE SUBJECT and display column headers for each variable defined in the column statement?

                  A. Proc Report;
                  column site subject trt age gender race;
                  define site/order 'Site';
                  define subject/order 'Subject';
                  define trt/'Treatment';
                  define age/'Age';
                  define gender/'Gender';
                  define race/'Race';
                  run;
                  B. Proc Report;
                  column site subject trt age gender race;
                  define site/order style(header)={'Site'};
                  define subject/order style(header)={'Subject'};
                  define trt/style(header)={'Treatment'};
                  define age/style(header)={'Age'};
                  define gender/style(header)={'Gender'};
                  define race/style(header)={'Race'};
                  run;
                  C. Proc Report;
                  column site subject trt age gender race;
                  define site, subject, trt, age, gender, race;
                  y site subject;
                  title 'Site Subject Treatment Age Gender Race';
                  run;
                  D. Proc Report;
                  column site subject trt age gender race;
                  define site/'Site', subject/'Subject',
                  trt/'Treatment', age/'Age', gender/'Gender',
                  race/'Race'; run;


                  Question #5

                  What is the primary purpose of programming validation?

                  A. Ensure that the output from both the original program and the validation program match.
                  B. Document all specifications pertaining to programmed output and ensure all were reviewed during the programming process.
                  C. Justify the means used to accomplish the outcome of a program and ensure its accurate representation of the original data.
                  D. Efficiently ensure any logic errors are discovered early in the programming process.


                  Solutions:

                  Question #1
                  Answer: D
                  Question #2
                  Answer: C
                  Question #3
                  Answer: D
                  Question #4
                  Answer: A
                  Question #5
                  Answer: C

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